A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.

Image Caption: CRISPR-Cas9 library identified XPR1 as a potential gene regulating autophagy. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Elenagen plus gemcitabine improves overall survival in platinum resistant ovarian cancer without increasing toxicity in Phase ...

Hdy-7 directly binds to TrxR1/2, triggering ROS accumulation and p53 activation. Activated p53 negatively regulates mTORC1 signaling, which is one of the major kinases responsible for the ...

Current status of physicians’ perception of HCC conversion/downstaging therapy: A nationwide survey in China. A multicenter, phase 2 study of atezolizumab plus bevacizumab (atezo+bev) combination ...

Mucin 16–Directed Therapy in Pediatric Sarcomas: Case Evidence of Ubamatamab Efficacy in Epithelioid Sarcoma and Its Implications for Other Sarcoma Subtypes Eligible patients had metastatic PDAC and ...

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste. This process, known as autophagy, is like a ...