BOSTON--(BUSINESS WIRE)--Karuna Pharmaceuticals, focused on targeting muscarinic receptors for the treatment of disorders marked by psychosis and cognitive impairment, today announced the completion ...
Please provide your email address to receive an email when new articles are posted on . Cobenfy is the first antipsychotic medication to treat schizophrenia by targeting cholinergic receptors. The ...
The cholinergic hypothesis of Alzheimer disease tends to elicit a yawn from scientists who reserve their excitement for anti-amyloid treatments or more radically new biologic approaches such as ...
The effects of continuous exposure to carbamylcholine (CbCho) on regulation and stabilization of acetylcholine receptors (AcChoR) were studied in cell cultures of G8, a continuous mouse muscle cell ...
An impressive data set that appeared yesterday in Neuron shows that a specific M1 muscarinic receptor agonist can reverse both cognitive deficits as well as the amyloid and tau pathology in the ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 84, No. 10 (May 15, 1987), pp. 3467-3471 (5 pages) In electrophysiological studies using the rat hippocampal slice ...
A protein that regulates the growth of neurons by transporting key metabolic enzymes to the tips of neural cells has been identified by an international team of researchers. Their findings open up new ...
Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated. Several single ...
Xerostomia (dry mouth) is a condition commonly encountered in clinical practice that can lead to multiple oral and systemic health problems. This condition has several potential etiologies, including ...
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