A promising approach is to leverage the intrinsic capabilities of bacterial toxins like diphtheria toxin (DT) to deliver a potent cytotoxic enzyme into cells with an associated membrane translocation ...

Examples of toxins of biological origin include Diphtheria Toxin, Tetrodotoxin ... eye, skin and mucous membranes, inhalation of toxin powder or aerosol inadvertently generated, or by needlestick ...

These toxins provide new tools for precision cancer medicine, bringing us closer to the elusive “magic bullet.” In addition, ...

a membrane can easily suffocate a child. If the toxin enters the blood stream, other organs can be damaged. 6. Even with treatment, the overall fatality rate for diphtheria is about 10% ...

Toxin-producing Corynebac­terium diphtheria usually causes two types ... in changes in voice and difficulty in breath­ing. The membrane may extend backward towards the lung and may partially ...

We are currently focusing on diphtheria and anthrax toxins, applying a variety of methods to generate detailed models of each step in toxin action. How these structurally unrelated toxins insert into ...

In recent years, quantitative real-time PCR tests have been extensively developed in clinical microbiology laboratories for routine diagnosis of infectious diseases, particularly bacterial ...

It is increasingly evident that membrane-damaging proteins ... ultimately benefiting toxin-expressing pathogens. These two types of responses are not expected to always be mutually exclusive ...

(1) Most QWERTY computer keyboards use a single rubber-like membrane underneath the keys that makes contact with a circuit board when the key is fully depressed. Also called a "dome switch ...

The most common symptom is a thick gray coating on the throat and tonsils. Symptoms of respiratory diphtheria are: Symptoms ...

If you're keen to save on your setup, the best membrane keyboards can help you stay nimble on the battlefield without breaking the bank. These decks won't hold up to their premium mechanical ...