G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...
The interplay between G protein-coupled receptors (GPCRs) and fatty acid metabolism is emerging as a pivotal aspect in the pathogenesis and treatment of type 2 diabetes. Receptors such as free fatty ...
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Tectonic Therapeutic Appoints François Nader, M.D., as Chair and Independent Director of the Board
Tectonic Therapeutic, Inc. (NASDAQ: TECX) (“Tectonic”), a clinical-stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the ...
Researchers analyzed the thermodynamics of doxepin binding to the histamine H1 receptor. The findings highlight the ...
About Septerna Septerna, Inc. is a clinical-stage biotechnology company with a world-class team of GPCR experts and drug developers advancing cutting-edge science to unlock the full potential of GPCR ...
A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors (GPCRs). This research offers ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
GPCRs represent one of the most important yet technically challenging classes of drug targets, largely due to difficulties in producing stable, native like antigens and generating high-quality ...
Ainnocence's breakthrough in GPCR antibody design represents a landmark advancement in the field. The company has successfully mapped the entire GPCR protein family sequences along with their highly ...
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