Renowned visionary English physician William Harvey wrote in 1651 about how our blood contains all the secrets of life. “And so I conclude that blood lives and is nourished of itself and in no way ...

A genetic variant is likely putting some children suffering with myocarditis—inflammation of the heart muscle—at higher risk of developing heart failure, which can be fatal, according to a study ...

Although you may not think of children when you imagine someone with heart problems, congenital heart defects are actually the most common birth defect in the U.S., occurring in about 1% of births.

A new gene therapy can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the amount of blood the heart can pump and dramatically improves ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...