The discovery of systemic disease related to raised tissue and serum immunoglobulin G4 (IgG4) is changing diagnostic and therapeutic practice in many medical specialties. Orbital inflammation remains ...

"…IgG4 has a remarkable stability, which makes it potentially useful as a prognostic marker. We suggest that measuring serum IgG4 levels could help physicians and ...

They could be doing better, at least in Europe. Data from 14 centers revealed moderate adherence to treatment guidelines, partial adherence to follow-up assessment, and poor adherence to monitoring ...

SAN JUAN, Puerto Rico — A small but significant percentage of patients with Graves' disease show elevated plasma levels of immunoglobulin G4 (IgG4), suggesting the presence of a novel subtype of the ...

Advances Amgen's Leadership in CD19 Directed, B-Cell Depletion Therapies for Serious Autoimmune Diseases Including NMOSD, IgG4-RD and gMG THOUSAND OAKS, Calif., April 3, 2025 /PRNewswire/ -- Amgen ...

Inebilizumab-cdon, a monoclonal antibody that depletes B cells, reduces the risk for flares without showing any new safety signals in patients with immunoglobulin G4-related disease (IgG4-RD) who have ...

IgG4-related disease is an autoimmune disorder affecting millions and has no established cure. Previous research indicates that T cells, a major component of the immune system, and the immunoglobulin ...

Anti-C1q antibodies were present among 74.3% of patients with immunoglobulin G4-related disease. Anti-C1q antibodies are highly prevalent among patients with immunoglobulin G4-related disease (IgG4-RD ...

In a recent study published in Science Immunology, researchers evaluated immunoglobulin G (IgG) responses to coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccinations. Study: ...

People with muscle-specific kinase myasthenia gravis appear to have more active antibody responses in general, the study found. People with muscle-specific kinase (MuSK) myasthenia gravis (MG) have ...

In a recent focus piece published in Science Immunology, a researcher emphasized the need to reconsider messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination strategies in ...