Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to be associated with neurodegenerative disorders. Corresponding author Kai ...

Insulin is one of the most potent and pleiotropic hormones in the body, regulating a myriad of physiological processes. However, perhaps none is best studied as its role in regulating glucose ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Rutgers Robert Wood Johnson Medical School and collaborating institutions have found that overnutrition leads to insulin resistance and metabolic disorders through increased activity of the ...

Protein intake influences far more than muscle mass; it shapes vascular function and pancreatic insulin dynamics over time.

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

The gut–glucose connection arises from interactions between gut microbes, hormones, and nutrient digestion. The human gut ...

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, ...