Neurons exposed to chronic iron overload do not simply die on contact. Instead, they enter a weakened, primed state that ...

Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer's and Parkinson's diseases are the most common; in the United States alone, the Alzheimer's Disease ...

A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and necroptosis—early in ischemic stroke recovery, exacerbating brain injury. This discovery ...

Recently discovered genetic mutations, modern diagnostic techniques, and fresh approaches to therapy change the outlook on hemochromatosis. Ben, age 46, visited his primary-care clinician with ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

Study reveals liraglutide's potential to regulate iron metabolism and improve glucose tolerance in a mouse model of hereditary hemochromatosis and obesity. Study: Liraglutide Impacts Iron Homeostasis ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

Iron overload, characterized by elevated serum ferritin levels, has long been associated with various systemic complications, yet its impact on skeletal health has not been as well understood. A ...