Atavistik Bio to present the discovery and characterization of novel allosteric JAK2 V617F selective inhibitors that suppress mutant-dependent ...

Off-label use of JAK inhibitors can prove beneficial in the treatment of several dermatologic conditions. Casey Butrus, PharmD: I wanted to bring back up the mechanism of action of the topical JAK ...

The Phase II OCULE-01 study in uveal melanoma started in March 2025, the PULMO-01 study in non-small cell lung cancer (NSCLC) started in May 2025 and the HEMA-MED Phase I/II study in myelofibrosis ...

PARIS — In a study that employed change in inflammatory biomarkers as a primary endpoint, hair regrowth with ritlecitinib, a dual JAK3/TEC inhibitor, was observed across three types of cicatricial ...

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We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. JAK inhibitors inhibit a broader cytokine profile than ...

Use of Janus kinase (JAK) inhibitors is associated with a nearly fourfold increase in risk of acne compared with placebo, according to an analysis of 25 JAK inhibitor studies. Acne has been reported ...

Dr Rosmarin illustrates treatment management of vitiligo with the use of JAK inhibitors. David Rosmarin, MD: Our JAK inhibitors have shown the most promise. Ruxolitinib cream 1.5% twice a day has gone ...

Please provide your email address to receive an email when new articles are posted on . Janus kinase inhibitors have delivered on some, but not all, of the promises that were expected of them upon ...

Watch out, Incyte: Leo Pharma’s topical JAK inhibitor is catching up. In a late-stage trial in moderate to severe chronic hand eczema, Leo Pharma's delgocitinib cream met its primary and secondary ...

ORLANDO -- More than 40% of patients with longstanding prurigo nodularis (PN) had significant improvement within 3 months of ...