The chicken major histocompatibility complex (MHC) represents a compact and evolutionarily distinct genomic region that plays a critical role in orchestrating adaptive immunity. Characterised by a ...

The immune system relies on a fine-tuned balance between the generation of peptide antigens and their presentation to cytotoxic T cells via Major Histocompatibility Complex (MHC) class I molecules.

Immunotherapy, which uses the body's own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it. Thus, cancer researchers are seeking new ways to ...

In this study, patients with multiple sclerosis (MS) and the experimental autoimmune encephalomyelitis (EAE) mouse model of MS exhibited an accumulation of Th17 cells in the small intestine.