Tumor cell deaths can benefit tumors. A paradox? Not at all. If, for example, a dying tumor cell undergoes necroptosis, it can release inflammatory factors that can enhance or diminish antitumor ...

When they find themselves trapped in an amyloid-ridden mouse brain, transplanted human neurons meet an untimely, necrotic demise. While this had been known before, a new-and-improved xenograft model ...

Alzheimer’s disease is characterized by a progressive loss of nerve cells leading to a decline in memory and cognition. Now, a new study by a team of researchers at KU Leuven and VIB explored the ...

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide. A landmark WEHI study has ...

Necroptosis is critical for regulating intestinal epithelial cells (IECs). Butyric acid (BA), produced during intestinal microbial metabolism, protects the intestinal epithelial barrier. However, ...

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early ...

BUFFALO, N.Y. — Research suggests one of the many ways cancer can spread is an explosive form of cell death known as necroptosis. This regulated self-destruction purges cancerous and other diseased ...

Clonal hematopoiesis of indeterminate potential (CHIP): Outcomes and adverse events in patients with solid tumors. Upstream regulation of neurotransmitter signaling genes in metastatic colorectal ...

A RAS-independent biomarker panel pedicts response to MEK-inhibitors in colorectal cancer. Development and validation of a predictive score to identify K-Ras wild-type (WT) metastatic colorectal ...

Alzheimer's disease is characterized by a progressive loss of nerve cells leading to a decline in memory and cognition. A team of researchers at KU Leuven and VIB explored the molecular sequence of ...