A recent study published in Frontiers in Immunology discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma. Study: Mechanisms ...

In a recent study published in Scientific Reports, researchers examined the role of specific gut microbes in the secretion of cytokines by peripheral blood mononuclear cells (PBMCs), monocyte-derived ...

A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants ...

Asthma is a chronic respiratory condition marked by airway inflammation, narrowing, and episodes of wheezing, coughing, and shortness of breath. It affects millions of people worldwide and continues ...

Dupilumab (interleukin-4Rα; antibody binds to interleukin-4Rα, inhibiting interleukin-4 and interleukin-13 signaling in hematopoietic cells [e.g., B cells, CD4+ helper T cells, and eosinophils], ...

Obesity-associated asthma (OAA) is a distinct asthma phenotype shaped by complex, bidirectional interactions among immunity, metabolism, respiratory mechanics, and microbiome, according to research ...

Although interleukin-23 has been implicated in the pathogenesis of asthma, in this randomized, controlled trial involving adults with severe asthma, inhibition of interleukin-23 signaling with the ...

Please provide your email address to receive an email when new articles are posted on . Sex and gender can influence the pathogenesis, clinical course, diagnosis, treatment and management of asthma, ...

A bioengineered lung model showed that the physical force of airway narrowing contributes to tissue remodeling in asthma, ...