Psychologists do have a name for this relationship between the Rams and 49ers: the Chameleon Effect. Kyle Shanahan and Rams head coach Sean McVay nonconsciously (I think) mimic each other — postures, mannerisms, assistant coaches, players, and plays. Everything.

Here's everything you need to know when the Los Angeles Rams play the San Francisco 49ers Week 10 of the 2025 NFL season.

The San Francisco 49ers are looking to string two wins together for the first time since starting 3-0 as they host the Los Angeles Rams in Week 10.  It’ll be a

The NFC West will be in the spotlight when the Los Angeles Rams visit the San Francisco 49ers, in a battle of division rivals that will have a heavy impact on the standings.

This is usually a very close matchup when they play the San Francisco 49ers. The Rams lost by three points to them last season, while winning by only six points in the meeting before that. Still, L.A. is 6-2 ATS this season and 2-1 ATS on the road.

When the San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee injury, star tight end George Kittle said it was time for the offense to step up and score at least 30 points a game.

Everything you need to know about the NFL match between San Francisco 49ers and Los Angeles Rams, as well as kick-off time and team news

TE-sets has reshaped their offense, explores the high stakes of this matchup in the NFC West title race, and dives into what the Rams learned from their Week 5 loss that could help flip the scri

The latest edition of Newsweek Sports Betting 📩 breaks down Seahawks-Rams, which headlines a massive Week 11 slate.

The San Francisco 49ers have received some very positive injury news entering a Week 11 clash with NFC West divisional rival Arizona. Fans will be ecstatic to learn that the news has officially broken that quarterback Brock Purdy will return to the starting role at signal caller for the 49ers this weekend after missing six games due to injury.