Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...

T cell receptors (TCRs) are fundamental to the adaptive immune system, playing a pivotal role in recognising and responding to pathogenic challenges. Generated through the process of V(D)J ...

Turning a decades-old dogma on its head, new research from scientists at UC San Francisco and Stanford Medicine shows that the receptor for oxytocin, a hormone considered essential to forming social ...

A poorly characterized protein, historically thought to be a chaperon or enzyme, may actually be a key player in prostate cancer. In a systematic CRISPR screen, scientists from Arc Institute, UCSF, ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a ...

Researchers at the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine have been awarded more than $15 ...

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, ...

Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...

Our sense of smell seems to be the most complicated, and as such it’s the least understood. To help shed some light on the system, researchers at Rockefeller University have taken the first ...

Bitter taste receptors inside cancer cells have been found to be activated in the presence of anti-cancer drugs. Shutting ...