Activating the GPR133 receptor with a small molecule can rebuild bone from within, offering a new direction for osteoporosis ...
In most developing tissues, signals called morphogens act like lighthouses, guiding nearby cells toward their fate and ...
News Medical on MSN
TRPM1 loss drives rhythmic activity across retinal diseases
Rhythmic electrical activity in the retina (known as pathological oscillations) has been observed in several eye diseases, ...
Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...
Nitrogen signal transduction plays a pivotal role in maintaining cellular metabolic balance by integrating environmental cues and internal nutrient levels. At the heart of this coordination are PII ...
Edited by: Karen Young Kreeger N. Funayama, F. Fagotto, P. McCrea, B.M. Gumbiner, "Embryonic axis induction by the armadillo repeat domain of b-catenin: Evidence for intracellular signaling," Journal ...
Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2
In recent years, immune checkpoint therapy headed by programmed death receptor 1 (PD-1) and programmed death receptor-ligand 1 (PD-L1) has been proven to be safe and effective. However, clinical ...
Edited by: James Kling P.A. Hoodless, T. Haerry, S. Abdollah, M. Stapleton, M.B. O'Connor, L. Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in ...
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