The sodium–chloride cotransporter (NCC) is a protein dimer central to sodium handling by the kidney and is the target of an important class of drug for high blood pressure called thiazide diuretics.

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for kidney ...

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for kidney ...