Stopping sedation each day may reduce the time people spend on a ventilator, probably reduces the number who die, and probably reduces the time people spend in intensive care and hospital, compared to ...

Compared with an inactive (dummy) treatment, aciclovir and penciclovir creams probably speed up cold sore healing by about one day without increasing the risk of unwanted events. Compared with each ...

This review shows that in subacute (medium-term) or persisting neck pain, at closest to 12 weeks follow-up, massage compared to a 'dummy' massage probably results in little to no difference in pain, ...

Nicotine e-cigarettes, commonly known as vapes, are more effective in helping people quit smoking than many conventional methods such as nicotine gums and patches and quitting with behavioural support ...

Our Handbooks describe the process of preparing and maintaining diverse types of systematic reviews. Handbooks are updated regularly to reflect advances in systematic review methods and in response to ...

We reviewed the evidence about the effect of exercise therapy on pain, disability, patient satisfaction, and quality of life among people with neck pain. Neck pain is common; it can limit a person's ...

During an asthma attack, the airways (tubes in the lungs) narrow making breathing difficult. The initial response to an asthma attack is to treat with a drug that can open up the airways and make ...

Leg cramps are experienced as sudden, intense involuntary contractions of the leg muscles. They are a common problem in pregnancy, especially in the third trimester. They are painful and can interfere ...

The aim of this Cochrane Review, first published in 2007, was to summarise research on immunising healthy children up to the age of 16 with influenza vaccines during influenza seasons. We used ...

Viral warts are a common skin disease, most frequently affecting the hands and feet, caused by the human papilloma virus. While warts are not harmful and usually go away in time without any treatment, ...

Compared to placebo, cold therapy may improve blood loss, pain, knee range of motion and short-term swelling after total knee replacement (TKR). We are less certain of its effect on blood transfusions ...

We reviewed the evidence about the effect of magnesium supplements on muscle cramps, and included the widest possible range of studies. This meant including studies on anyone suffering muscle cramps, ...