Objective: The aim of this study was to compare the antihypertensive efficacy and tolerability of the calcium channel antagonist amlodipine besylate versus the angiotensin II type 1 receptor ...

The calcium channel blocker amlodipine and angiotensin ll receptor blocker losartan, with or without hydrochlorothiazide (HCTZ), were compared for the treatment of mild to moderate hypertension in ...

In a closed state, the two arms are parallel; when the structure opens, the arms fold out to form an angle of up to 90°. "As a result of this large conformational change, the fluorescence signal also ...

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune ...

We used a two-step extraction process to isolate as diverse chemical mixtures as possible," says Georg Braun, postdoctoral researcher in Beate Escher's working group and first author of the study.

Small molecules are essential for developing effective medicines, but their structural complexity and material behaviour ...

Often known as the central science, it is a creative discipline chiefly concerned with atomic and molecular structure and its change, for instance through chemical reactions. One electron σ-bonds ...

The Department of Chemical and Biological Engineering at Northwestern University is pioneering transformational discoveries in synthetic biology, biotechnology, medicine, complex systems, energy, ...

Capital structure describes the mix of a firm's long-term capital—a mix of debt and equity—that it uses to fund its ongoing operations and future growth. A company's capital structure is ...

Organic chemistry is the study of the structure, properties, composition ... Petroleum is also the raw material for many chemical products (e.g., pharmaceuticals, solvents, fertilizers, pesticides, ...

Highlights of prescribing information: Norvasc (amlodipine besylate). Yeboah J, Bertoni A, Qureshi W, et al. Pedal edema as an indicator of early heart failure in the community: prevalence and ...