Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Scientists mapped hidden DNA switches in brain support cells to understand how gene control may influence Alzheimer’s disease ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

The working model shows the known and novel functions of OTULIN. OTULIN regulates proteostasis, cell death, inflammation, and cell survival/development. The sporadic Alzheimer’s disease (sAD2.1) iPSC ...

When most of us think of DNA, we have a vague idea it's made up of genes that give us our physical features, our behavioral ...

A shared molecular signature of Alzheimer’s appears across populations once studied in isolation. Alzheimer's disease (AD) ...