The actress, who stars alongside Demi Moore in the body horror film, says it took "probably a year" for her skin to recover.

Margaret Qualley really felt the effects of “The Substance.” The actress, 30, recently appeared on Josh Horowitz’s “Happy Sad Confused” podcast and spoke about how wearing extensive prosthetics to shoot the bloody horror film took a toll on her skin.

In The Substance, Hollywood star Elisabeth Sparkle (Demi Moore) is fired from her aerobics show when she turns 50. This leads her to seek out a drug called The Substance. After taking the drug, Elisabeth births a younger version of herself who she shares a consciousness with - the catch is she has to alternate living as each every seven days.

Margaret Qualley reflected on the long-term effects she endured due to the prosthetics while playing Sue in The Substance.Speaking on the Happy Sad Confused podcast, on January 13, the

The actress spoke about dealing with acne caused by the movie makeup on Josh Horowitz's 'Happy Sad Confused' podcast

Margaret Qualley shares how prosthetics for The Substance left her face damaged, taking a year for full recovery.

Margaret Qualley is proving she’s a Hollywood force in her own right. As if her striking features, raven hair and charming smile weren’t enough to showcase that she was destined for the screen, her acting chops and rapidly growing resume should be.

The film The Substance, directed by Coralie Fargeat, continues to be talked about, in particular thanks to the breathtaking performances of its main actresses. If Demi Moore won a Golden Globe for her remarkable role,