The products are being advertised as more affordable alternatives to blockbuster weight-loss drugs. Here’s what doctors think about them.

Ozempic is a medication for Type 2 diabetes that helps control blood sugar, with the added side effect of weight loss. Socialite and reality TV personality Kourtney Kardashian has a natural alternative to Ozempic that she is going gaga over.

While both berberine and Ozempic may lead to weight loss, they are very different things. It’s “inaccurate and misleading” to call berberine “nature’s Ozempic,” Dr. Ali says, noting that they work differently in the body and have very different weight loss results.

Natural supplements have “very mild effects” on weight loss based on what Dr. Ali has seen. There is some data to suggest that saffron, green tea, or turmeric can have a slight impact on GLP-1 production, he says, but again, it's not a ton.

Kourtney Kardashian’s new “GLP-1 Daily” pill is the latest product to capitalize on the weight loss drug craze.

Prescribed medications like Ozempic and Wegovy can be expensive and hard to find, leading to a rise in popularity of natural weight-loss alternatives — but do they really work, and are they safe? NBC’s Emilie Ikeda reports and gastroenterologist Dr.