Aidan O’Brien’s Betfred 2000 Guineas hope Twain has been declared a major doubt for Saturday’s opening Classic of the season at Newmarket.

The drug maker said it is ‘firmly committed to investing and growing in the US’ amid potential import tariffs on the pharmaceutical industry.

Human rights laws could still be an obstacle to removing foreign sex offenders from the UK, the Home Secretary said, as she suggested changes could be needed to the way the rules are interpreted.

Yostin Andres Mosquera is accused of killing Albert Alfonso and Paul Longworth in London and dumping their remains near the Clifton ...

Andover Cricket Club, sponsored by Nordlock, rounded off their pre-season programme with victories for their first and second XIs and a defeat for a young third team, writes Matt Hooper . Andover's ...