Acalabrutinib (Calquence; AstraZeneca) demonstrated a more modest ORR of 40% in a smaller 25-patient cohort, with median progression-free survival (PFS) of 3.2 months. While less robust than ...

Hearing impairment is a common nonmotor manifestation of Parkinson disease, often involving high-frequency hearing loss.

Parkinson's disease is more common among individuals with a higher socioeconomic status and in the northern provinces of the Netherlands. In the southern provinces, Parkinson's occurs less frequently.

Parkinson’s disease, often associated with its hallmark physical symptoms of tremors or changes in movement, can also affect your communication and ability to keep up in conversation. “In some cases, ...

Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that something isn't right. A classic example is Lewy bodies (LBs), abnormal clumps ...

About 1 million Americans suffer from Parkinson’s disease, with around 90,000 new cases diagnosed each year, according to the Parkinson’s Foundation. The chronic, degenerative brain disorder destroys ...

Parkinson’s disease, a progressive nervous system movement disorder, weakens and damages nerve cells in parts of the brain. This leads to declining production of brain chemicals, says Karen M. Thomas, ...

A familiar mouth bacterium best known for causing cavities may also be quietly influencing the brain. Scientists found that when this microbe settles in the gut, it produces compounds that can travel ...

Pro Football Hall of Famer Brett Favre shared an update on his health a year after revealing he was diagnosed with Parkinson's, saying he is in the early stages of the disease. Favre first revealed he ...

Amy Lindberg spent 26 years in the Navy and she still walked like it—with intention, like her chin had someplace to be. But around 2017, her right foot stopped following orders. Lindberg and her ...

EDITOR’S NOTE: The podcast Chasing Life With Dr. Sanjay Gupta explores the medical science behind some of life’s mysteries big and small. You can listen to episodes here. The “Shaking Palsy.” Those ...

Your daily step count might reveal more than just your fitness progress. In a study of nearly 95,000 adults wearing activity trackers, lower step totals were linked to later Parkinson’s diagnoses.