Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a ...

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy ...

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a ...

Parkinson’s disease (PD) has been recently associated with the excessive expression of matrix metalloproteinase 3 (MMP3). One of the major challenges in treating PD is to effectively detect and ...

Assessing α-synuclein SAA kinetic measures might aid in the diagnostic differentiation of Parkinson's disease from progressive supranuclear palsy with Lewy body co-pathology. Furthermore, faster ...

The 3 different types of tachycardias associated with accessory pathways are shown in Figure 3. The most common type (Figure 3 A) results from an electric circuit that travels from the atria through ...

Their new study, published in Analytical Chemistry, shows that artificial intelligence can detect Parkinson’s disease by analyzing volatile organic compounds (VOCs) in ear canal secretions with over ...

In patients with Parkinson disease (PD) and comorbid mood dysfunction, psilocybin-assisted therapy is well-tolerated and associated with sustained improvements in depression, anxiety, motor ...

For more information about the Phase 1/2 clinical trial, please visit www.clinicaltrials.gov (NCT07011771). About Parkinson’s disease associated with GBA mutations (PD-GBA) ...

Autophagy Autophagy is a key cellular mechanism in protein homeostasis on which many of the pathogenic pathways involved in PD eventually converge (98). Autophagy plays a role in α-synuclein handling, ...

Parkinson's disease (PD) is a common neurodegenerative disorder, affecting 9.4 million people worldwide (Maserejian et al., 2020). Patients display muscle rigidity, bradykinesia, and resting tremor; ...