The FDA updated the indication of the JAK inhibitor upadacitinib (Rinvoq) in inflammatory bowel disease (IBD) to account for cases where a patient may not be appropriate for a TNF blocker, drugmaker ...

A meta-analysis showed no significant differences between JAK inhibitor use and TNF antagonist use in terms of the risk for serious infections or malignant neoplasms in patients with immune-mediated ...

Maddie Fisher is a writer, journalist and game developer. She was born and raised on the east coast, having started working in games journalism over fifteen years ago. She tends to enjoy musical ...

The gaming pros at TheGamersJoint celebrate a surprise content drop that adds even more life to Jak and Daxter. Thousands of Americans told to avoid refueling cars Fetterman Delivers ‘Reality Check’ ...

Jake brings two decades of experience with him, having covered major industry events, breaking news, one-on-one interviews, and more. When he's not playing World of Warcraft, he's usually on the hunt ...

A new Jak and Daxter game is in the works at God of War developer Santa Monica Studios, or so PlayStation fans hope. Based on reporting so far, there appears to be a few different games in the works ...

The gaming pros at TheGamersJoint celebrate a massive fan update for Jak and Daxter on PS5. Mary Trump issues warning on long-term impact of Donald Trump move Six sleep warning signs that indicate ...

Some previous studies, including the ORAL Surveillance randomized trial, have shown moderately greater cancer risks with JAK inhibitors versus TNF inhibitors. But some other analyses of real-world ...

GameSpot may get a commission from retail offers. This week's Triple- Initiative covered a wide range of genres, but for anyone looking for a retro-inspired platformer, then Duskfade was likely the ...

Ruxolitinib cream shows comparable efficacy to systemic therapies in reducing disease severity in moderate atopic dermatitis, with significant BSA reduction over 7.4 months. Abrocitinib demonstrates ...

Prime Video’s partnership with Starz continues as the latter has launched a Starz-BET+ bundle on the Amazon-owned streaming platform for $15.99 per month — marking savings of approximately 30%. The ...

JAK inhibitors, a new class of tsDMARDs, have shown superior efficacy in RCTs for RA compared to other biologics. Real-world studies highlight JAK inhibitors' benefits in clinical disease activity, ...