Hundreds of Jenin residents left their homes on Thursday, prompted by messages from drones fitted with loudspeakers, witnesses said, as the military demolished a number of houses on the third day of a major operation in the West Bank city.

"On the directive of the Security Cabinet, the IDF, the ISA, and the Israel Police have today begun a...military operation to defeat terrorism in Jenin," Netanyahu said.

The West Bank city of Jenin was the target of an ongoing Israeli "anti-terror" operation that claimed the lives of at least 10 Palestinians and injured as many as 40 others.

Prime Minister Benjamin Netanyahu said the assault on Jenin would be “extensive and significant,” as the military erected new checkpoints across the West Bank.

Operation Iron Wall begins with drone strikes on terror infrastructure; large numbers of troops enter city; 10 Palestinians said killed, 40 wounded

Israeli security forces backed by helicopters raided the volatile West Bank city of Jenin on Tuesday, killing at least eight Palestinians in what Prime Minister Benjamin Netanyahu called a "large-scale and significant military operation." Fadi Al-Saadi's brother was killed in the raid. This video contains distressing images.

Israel says it has killed two armed men, suspected of carrying out a shooting attack that killed three Israelis in the occupied West Bank earlier this month. Qutaiba Shalabi and Mohammed Nazzal were killed after a fierce gun battle with Israeli forces on Wednesday night in Burqin,

At least 10 people have been killed in the raids, and more than 40 wounded, according to the Palestinian Health Ministry. Dozens have been arrested, Palestinian officials told the Wafa news agency.

Gunfire and explosions rocked the Jenin area of the occupied West Bank on Wednesday, an AFP journalist reported, as the Israeli military kept up a large-scale raid for a second day.