德国慕尼黑大学Florian Gaertner团队在Nature发表题为Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis的研究论文。研究人员揭示了浆细胞样树突状细胞（pDCs）通过监测骨髓中的凋亡巨核细胞（MKs ...
Platelets play an essential role in wound healing. Underproduction can cause devastating bleeding, while overproduction increases the deadly risk of thromboses. Maintaining a constant level of ...
The researchers published their findings in the journal Nature. To find out how MKs develop (megakaryopoiesis), the lead authors—namely, Florian Gärtner, Hellen Ishikawa-Ankerhold, Susanne Stutte and ...
An LMU team working with international colleagues has discovered how certain immune cells control the formation of new megakaryocytes from progenitor cells in bone marrow. They discovered that the ...
Ketones for chemoChemotherapy can reduce platelet counts in patients with cancer, in turn limiting treatment efficacy. Xie et al. report that ketogenesis-induced β-hydroxybutyrate mitigated this ...
Myeloid leukemia associated with Down syndrome (ML-DS) has a unique molecular landscape that differs from other subtypes of acute myeloid leukemia. ML-DS is often preceded by a myeloproliferative ...
It is urgent to find out an alternative therapy for Kawasaki disease (KD) since around 20% patients are resistant to intravenous immunoglobulin (IVIG) or aspirin. Tanshinone IIA is the active ...
Mochida T, Fujimoto N, Asahina M, Asano S, Araki S, Inukai N, Hotta A Morisaka H*, Yoshimi K*, Okuzaki Y*, Gee P, Kunihiro Y, Sonpho E, Xu H, Sasakawa N, Naito Y ...
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