A peer-reviewed neurology, neurosurgery and psychiatry journal publishing the latest research and reviews on the entire genre of neurological sciences.

Sue Fletcher-Watson holds a Personal Chair in Developmental Psychology at the University of Edinburgh, and is Director of the Salvesen Mindroom Research Centre. She is interested in how children grow ...

Use of oral contraceptives is a recognised but infrequent cause of chorea. This type of chorea has usually been considered a reactivation of Sydenham’s chorea by an unknown mechanism. A patient ...

1 Farr Institute of Health Informatics, University College London, London, UK 2 Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences, University of Manchester, Manchester Academic ...

Stroke is a heterogeneous syndrome caused by multiple disease mechanisms, but all result in a disruption of cerebral blood flow with subsequent tissue damage. This review covers the mechanisms ...

1 Alzheimer Centre and Department of Neurology, VU Medical Centre, Amsterdam, Netherlands 2 Department of Radiology VU Medical Centre 3 Department of Neurology, University Medical Centre St Radboud, ...

Background Staging of disease severity is useful for prognosis, decision-making and resource planning. However, no commonly used, validated staging system exists for amyotrophic lateral sclerosis (ALS ...

Introduction The association between chronic inflammatory demyelinating polyneuropathy (CIDP) and diabetes is uncertain despite important diagnostic and management implications. Methods We ...

A method was developed for making EMG recordings from the four individual muscles of the anterior abdominal wall. It was then demonstrated that these muscles have different and distinguishable actions ...

Correspondence to: Professor J Wardlaw, Department of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK; jmw{at}skull.dcn.ed.ac.uk Objectives: To determine the ...

Objectives: To determine the prevalence of dementia in people under the age of 65 in a large catchment area, and use these figures to estimate the number of younger people affected by dementia in the ...

Objective To retrospectively investigate safety and efficacy of nusinersen in a large cohort of adult Italian patients with spinal muscular atrophy (SMA). Methods Inclusion criteria were: (1) clinical ...