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1:35
Austin EMS urges people to carry more Narcan as overdoses grow harder to reverse
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Explaining massive acetaminophen overdose mechanisms does not mean therapeutic doses are toxic. When taken at standard recommended doses (under 3,000 to 4,000 mg daily for healthy adults), acetaminophen is metabolized safely through hepatic glucuronidation and sulfation pathways. Hepatotoxicity occurs when massive supratherapeutic doses saturate normal pathways, shunting drug metabolism to CYP2E1 and producing toxic levels of the metabolite NAPQI that deplete glutathione stores. Large epidemiolo
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A new synthetic opioid stronger than fentanyl has been found circulating in San Francisco. Authorities say four have been arrested following the overdose death of a 16-year-old, the first known victim of the drug that is so new it's not currently considered illegal in California and test kits do not detect it. Here's what to know. #tenderloin #sanfrancisco #sf #opioid #drug #fentanylcrisis #overdoseawareness #narcan #abc7news
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